They just have a different feel, either heavier or lighter (depending on the fabric obviously) and if you're feeling boujie, could even get them tailored with some nerdy Mod details like step-bottom (or "stepped hem"? I'm not sure what you'd call it) or epaulets on the cuff. Keep the shirt sort of neutral and it can be a good look.
On this subject, Adaptor have a set of two-tone trousers kicking around at the moment, the fabric of which is apparently "woven exclusively for Adaptor, and is available nowhere else!"
Feast your eyes. They've got burgundy/gold and blue/gold two tone, but with the important addition of a nice covered button flap-pocket.